1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide, 97%, Thermo Scientific Chemicals

Description

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3'-amino-3'-deoxyadenosine-5'-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide is used as a carboxyl activating agent and activate phosphate groups in phospho mono and di esters. It is used in peptide synthesis, 3′-amino-3′-deoxyadenosine-5′-di- and triphosphates and in the preparation of antibodies like immunoconjugates. It plays a vital role for immobilization of large biomolecules in association with N-hydroxysuccinimide. It is also used in the acylation of phosphoranes.

Solubility
Soluble in water.

Notes
Air sensitive. Incompatible with strong acids and strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1892-57-5
• Molecular Formula: C8H17N3
• Molecular Weight (g/mol): 155.245
• MDL Number: MFCD00044916
• InChI Key: LMDZBCPBFSXMTL-UHFFFAOYSA-N
• Synonym: 1-3-dimethylaminopropyl-3-ethylcarbodiimide, edac, 1-ethyl-3-3-dimethylaminopropyl carbodiimide, n1-ethylimino methylene-n3,n3-dimethylpropane-1,3-diamine, unii-rj5ozg6i4a, edci, 1,3-propanediamine, n'-ethylcarbonimidoyl-n,n-dimethyl, n-3-dimethylaminopropyl-n'-ethylcarbodiimide, rj5ozg6i4a, ethyldimethylaminopropyl carbodiimide
• PubChem CID: 15908
• IUPAC Name: 3-(ethyliminomethylideneamino)-N,N-dimethylpropan-1-amine
• SMILES: CCN=C=NCCCN(C)C

• Density: 0.885
• Boiling Point: 66°C to 68°C (1 mmHg)
• Flash Point: >110°C (230°F)
• Linear Formula: CH₃CH₂N=C=N(CH₂)₃N(CH₃)₂
• Refractive Index: 1.461
• Quantity: 5 g
• UN Number: UN2735
• Beilstein: 507429
• Sensitivity: Air and moisture sensitive
• Solubility Information: Soluble in water.
• Formula Weight: 155.24
• Percent Purity: 97%
• Chemical Name or Material: 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide

Safety and Handling

Product Identifier

• 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

Supplemental information

• MIXTURE LIST-Contains : 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide

RUO – Research Use Only