1,4-Dioxane, anhydrous, 99.8%, stab. with 1-3ppm BHT, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals

Description

1,4-Dioxane is used as a stabilizer for 1,1,1-trichloroethane and chlorinated solvents. It acts as a solvent for cellulose acetate, ethyl cellulose, benzyl cellulose, resins, oils, waxes, dyes, other organic and inorganic compounds. It acts as a substitute for tetrahydrofuran due to its higher boiling point and lower toxicity. Further, it is used as an internal standard for proton NMR spectroscopy in deuterium oxide. It plays an important role in liquid scintillation counting in biological procedures, and as a wetting and dispersing agent in textile processing. It is involved in the preparation of dimethylmagnesium by reacting with methylmagnesium bromide, and in the preparation of histological sections for microscopic examination.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

Chemical Identifiers

• CAS: 123-91-1
• Molecular Formula: C4H8O2
• Molecular Weight (g/mol): 88.106
• MDL Number: MFCD00006571
• InChI Key: RYHBNJHYFVUHQT-UHFFFAOYSA-N
• Synonym: dioxane, p-dioxane, 1,4-diethylene dioxide, diethylene ether, dioxan, 1,4-dioxacyclohexane, diethylene dioxide, dioxanne, di ethylene oxide, tetrahydro-p-dioxin
• PubChem CID: 31275
• ChEBI: CHEBI:47032
• IUPAC Name: 1,4-dioxane
• SMILES: C1COCCO1

• Melting Point: 11.8°C
• Color: Colorless
• Appearance: Colorless liquid
• Density: 1.034 g/cm³ at 20°C
• Boiling Point: 100°C to 102°C
• Quantity: 100 mL
• Flash Point: 12°C (54°F)
• Ignition Point: 375°C (707°F)
• Odor: Ether like
• Physical Form: Liquid
• Refractive Index: 1.422
• Assay Percent Range: 99.8%
• Vapor Pressure: 41 hPa (31mm Hg) at 20°C
• UN Number: 1165
• Beilstein: 102551
• Solubility Information: Miscible with water,most organic solvents,aromatic hydrocarbons and oils.
• Formula Weight: 88.11
• Concentration or Composition (by Analyte or Components): 1, 4-Dioxane, anhydrous
• Chemical Name or Material: 1, 4-Dioxane, anhydrous

Safety and Handling

Product Identifier

• 1,4-Dioxane

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Carcinogenicity Category 1B
• Serious eye damage/eye irritation Category 2
• Flammable liquid Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H225-Highly flammable liquid and vapour.
• H302-Harmful if swallowed.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.
• H350-May cause cancer.

Precautionary Statement

• P201-Obtain special instructions before use.
• P202-Do not handle until all safety precautions have been read and understood.
• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P233-Keep container tightly closed.
• P240-Ground/bond container and receiving equipment.
• P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
• P242-Use only non-sparking tools.
• P243-Take precautionary measures against static discharge.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P271-Use only outdoors or in a well-ventilated area.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P370+P378-In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
• P403+P233-Store in a well-ventilated place. Keep container tightly closed.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information

• MIXTURE LIST-Contains : 1,4-Dioxane

RUO – Research Use Only