1,8-Cineole, 99%, Thermo Scientific Chemicals

Description

Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant. It controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition. Eucalyptol is an effective treatment for nonpurulent rhinosinusitis. Eucalyptol reduces inflammation and pain when applied topically. It kills leukaemia cells in vitro.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant. It controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition. Eucalyptol is an effective treatment for nonpurulent rhinosinusitis. Eucalyptol reduces inflammation and pain when applied topically. It kills leukaemia cells in vitro.

Solubility
Soluble in water(3500 mg/L (at 21°C). Miscible with ether, alcohol, chloroform, glacial acetic acid, oils. Soluble in ethanol, ethyl ether; slightly soluble in carbon tetrachloride.

Notes
Store this chemical under refrigerated temperatures and away from mineral acids and bases. Store in a tightly closed container. Store in a dry, well-ventilated area.

Specifications

Chemical Identifiers

• CAS: 470-82-6
• Molecular Formula: C10H18O
• Molecular Weight (g/mol): 154.25
• MDL Number: MFCD00167977
• InChI Key: WEEGYLXZBRQIMU-UHFFFAOYSA-N
• Synonym: eucalyptol, cineole, 1,8-cineole, 1,8-cineol, cajeputol, 1,8-epoxy-p-menthane, eucalyptole, zineol, eucapur, terpan
• PubChem CID: 2758
• IUPAC Name: 2,2,4-trimethyl-3-oxabicyclo[2.2.2]octane
• SMILES: CC12CCC(CC1)C(C)(C)O2

• Melting Point: 1°C
• Density: 0.92
• Boiling Point: 176°C to 177°C
• Flash Point: 49°C (120°F)
• Assay Percent Range: 99%
• Refractive Index: 1.4575
• Quantity: 100 mL
• UN Number: UN3271
• Beilstein: 105109
• Merck Index: 14,3895
• Solubility Information: Soluble in water(3500mg/L (at 21°C). Miscible with ether,alcohol,chloroform,glacial acetic acid,oils. Soluble in ethanol,ethyl ether; slightly soluble in carbon tetrachloride.
• Formula Weight: 154.24
• Percent Purity: 99%
• Physical Form: Liquid
• Chemical Name or Material: Cineole

Safety and Handling

Product Identifier

• 1,8-Cineole

Signal Word

• Warning

Hazard Category

• Flammable liquid Category 3
• Skin sensitiser Category 1

Hazard Statement

• H226-Flammable liquid and vapour.
• H317-May cause an allergic skin reaction.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
• P362+P364-Take off contaminated clothing and wash it before reuse.

Supplemental information

• MIXTURE LIST-Contains : 1,8-Cineol

RUO – Research Use Only