1-Adamantanamine, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
15403867	Thermo Scientific Alfa Aesar H30076.06	5 g
15413867	Thermo Scientific Alfa Aesar H30076.14	25 g
15423867	Thermo Scientific Alfa Aesar H30076.22	100 g

Description

1-Adamantanamine acts as a catalyst in enantioselective strecker reaction of phosphinoyl imines. It is also useful for making adamantane derivatives, i.e. amantadine hydrochloride. It is used in the pharmaceutical industry as antiviral and an antiparkinsonian drug.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Adamantanamine acts as a catalyst in enantioselective strecker reaction of phosphinoyl imines. It is also useful for making adamantane derivatives, i.e. amantadine hydrochloride. It is used in the pharmaceutical industry as antiviral and an antiparkinsonian drug.

Solubility
Soluble in organic solvents. Insoluble in water.

Notes
Use only in a chemical fume hood. Keep away from sources of ignition. Incompatible with oxidizing agent.

Chemical Identifiers

• CAS: 768-94-5
• Molecular Weight (g/mol): 151.253
• InChI Key: DKNWSYNQZKUICI-UHFFFAOYSA-N
• PubChem CID: 2130
• IUPAC Name: adamantan-1-amine

• Molecular Formula: C10H17N
• MDL Number: MFCD00074732
• Synonym: amantadine, 1-adamantanamine, 1-adamantylamine, 1-aminoadamantane, adamantanamine, adamantylamine, aminoadamantane, amantidine, symadine, symmetrel
• ChEBI: CHEBI:2618
• SMILES: C1C2CC3CC1CC(C2)(C3)N

Specifications

• CAS: 768-94-5
• Molecular Formula: C10H17N
• Synonym: amantadine, 1-adamantanamine, 1-adamantylamine, 1-aminoadamantane, adamantanamine, adamantylamine, aminoadamantane, amantidine, symadine, symmetrel
• InChI Key: DKNWSYNQZKUICI-UHFFFAOYSA-N
• IUPAC Name: adamantan-1-amine
• PubChem CID: 2130
• Formula Weight: 151.25
• Chemical Name or Material: 1-Adamantanamine

• Melting Point: ∼200°C (sublimation)
• MDL Number: MFCD00074732
• Solubility Information: Soluble in organic solvents. Insoluble in water.
• SMILES: C1C2CC3CC1CC(C2)(C3)N
• Molecular Weight (g/mol): 151.253
• ChEBI: CHEBI:2618
• Percent Purity: 98%

Safety and Handling

Causes serious eye irritation, Harmful if swallowed, May cause respiratory irritation, Causes skin irritation

Serious eye damage/eye irritation (category 2), Acute toxicity (category 4), Specific target organ toxicity after single exposure (category 3), Skin corrosion/irritation (category 2)

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missing translation for 'rtecsNumber' : YD1925000

missing translation for 'tsca' : Yes

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• LONG-TERM AQUATIC HAZARD Chronic 3
• Serious eye damage/eye irritation Category 1
• Reproductive toxicity Category 2
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H302-Harmful if swallowed.
• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• H361-Suspected of damaging fertility or the unborn child.
• H412-Harmful to aquatic life with long lasting effects.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.

RUO – Research Use Only