1-Adamantanamine hydrochloride, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11410613	Thermo Scientific Alfa Aesar A12699.14	25 g
11420613	Thermo Scientific Alfa Aesar A12699.22	100 g
11430613	Thermo Scientific Alfa Aesar A12699.36	500 g

Description

1-Adamantanamine hydrochloride is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extra pyramidal reactions, and for postherpetic neuralgia. It is also used an NMDA-receptor antagoinst.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Adamantanamine hydrochloride is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extra pyramidal reactions, and for postherpetic neuralgia. It is also used an NMDA-receptor antagoinst.

Solubility
Soluble in water (50 mg/ml), ethanol (38 mg/ml at 25°C), chloroform (1:18), DMSO (38 mg/ml at 25°C), and methanol

Notes
Hygroscopic. Store in cool dry place in tightly closed container. With good ventilation. Store away from oxidizing agent and water/moisture.

Chemical Identifiers

• CAS: 665-66-7
• Molecular Weight (g/mol): 187.71
• InChI Key: WOLHOYHSEKDWQH-UHFFFAOYSA-N
• PubChem CID: 64150
• IUPAC Name: adamantan-1-amine;hydrochloride

• Molecular Formula: C10H18ClN
• MDL Number: MFCD00074723
• Synonym: amantadine hydrochloride, 1-adamantanamine hydrochloride, symmetrel, 1-aminoadamantane hydrochloride, amantadine hcl, adamantanamine hydrochloride, amazolon, midantan, midantane, mydantane
• ChEBI: CHEBI:2619
• SMILES: [H+].[Cl-].NC12CC3CC(CC(C3)C1)C2

Specifications

• CAS: 665-66-7
• Molecular Formula: C10H18ClN
• Beilstein: 4198854
• Synonym: amantadine hydrochloride, 1-adamantanamine hydrochloride, symmetrel, 1-aminoadamantane hydrochloride, amantadine hcl, adamantanamine hydrochloride, amazolon, midantan, midantane, mydantane
• InChI Key: WOLHOYHSEKDWQH-UHFFFAOYSA-N
• IUPAC Name: adamantan-1-amine;hydrochloride
• PubChem CID: 64150
• Formula Weight: 187.71
• Chemical Name or Material: 1-Adamantanamine hydrochloride

• Melting Point: 360°C
• MDL Number: MFCD00074723
• Merck Index: 14374
• Solubility Information: Soluble in water (50mg/ml),ethanol (38mg/ml at 25°C),chloroform (1:18),DMSO (38mg/ml at 25°C),and methanol
• SMILES: [H+].[Cl-].NC12CC3CC(CC(C3)C1)C2
• Molecular Weight (g/mol): 187.71
• ChEBI: CHEBI:2619
• Percent Purity: 99%

Safety and Handling

Harmful if swallowed

Acute toxicity (category 4)

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Recommended Storage : Ambient temperatures

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4

Hazard Statement

• H302-Harmful if swallowed.

Precautionary Statement

• P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.

RUO – Research Use Only