1-Trimethylsilylmethanol, 95%, Thermo Scientific Chemicals

Description

1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

Solubility
Fully miscible in water.

Notes
Store at 4°C. Incompatible with oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specifications

Chemical Identifiers

• CAS: 3219-63-4
• Molecular Formula: C4H12OSi
• Molecular Weight (g/mol): 104.224
• MDL Number: MFCD00004596
• InChI Key: ZQKNBDOVPOZPLY-UHFFFAOYSA-N
• Synonym: trimethylsilyl methanol, 1-trimethylsilylmethanol, hydroxymethyltrimethylsilane, methanol, trimethylsilyl, silane, hydroxymethyl trimethyl, hydroxymethyl trimethylsilane, trimethylhydroxymethylsilane, methanol, 1-trimethylsilyl, trimethylsilyl-methanol, acmc-209hrr
• PubChem CID: 76692
• IUPAC Name: trimethylsilylmethanol
• SMILES: C[Si](C)(C)CO

• Boiling Point: 121°C to 122°C
• Quantity: 5 g
• UN Number: UN1993
• Beilstein: 1731486
• Flash Point: 31°C (87°F)
• Solubility Information: Fully miscible in water.
• Formula Weight: 104.23
• Percent Purity: ≥98%
• Refractive Index: 1.419
• Density: 0.827
• Chemical Name or Material: 1-Trimethylsilylmethanol

RUO – Research Use Only