2,2,2-Trifluoroacetamide, 97%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11407117	Thermo Scientific Alfa Aesar A14451.14	25 g
11417117	Thermo Scientific Alfa Aesar A14451.22	100 g
11427117	Thermo Scientific Alfa Aesar A14451.36	500 g

Description

2,2,2-Trifluoroacetamide used in a convenient alternative to the Gabriel synthesis of primary amines from halides by N-alkylation followed by cleavage of the readily-hydrolyzed trifluoroacetyl group and for improved N-alkylation under phase-transfer conditions allowing successive alkylation with different alkyl groups.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,2,2-Trifluoroacetamide used in a convenient alternative to the Gabriel synthesis of primary amines from halides by N-alkylation followed by cleavage of the readily-hydrolyzed trifluoroacetyl group and for improved N-alkylation under phase-transfer conditions allowing successive alkylation with different alkyl groups.

Solubility
Soluble in water (460 g/L at 20°C), alcohol, ether, chloroform (partially), and methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong acids, strong bases and strong reducing agents.

Chemical Identifiers

• CAS: 354-38-1
• Molecular Weight (g/mol): 113.04
• InChI Key: NRKYWOKHZRQRJR-UHFFFAOYSA-N
• PubChem CID: 67717
• SMILES: NC(=O)C(F)(F)F

• Molecular Formula: C2H2F3NO
• MDL Number: MFCD00008008
• Synonym: trifluoroacetamide, acetamide, 2,2,2-trifluoro, unii-36mu16byfk, n-trifluoroacetamide, 2,2,2-trifluoro-acetamide, 36mu16byfk, trifluroacetamide, trifluoro-acetamide, snylgqhjptadtaetp@, pubchem12622
• IUPAC Name: 2,2,2-trifluoroacetamide

Specifications

• CAS: 354-38-1
• Boiling Point: 162°C to 164°C
• MDL Number: MFCD00008008
• Synonym: trifluoroacetamide, acetamide, 2,2,2-trifluoro, unii-36mu16byfk, n-trifluoroacetamide, 2,2,2-trifluoro-acetamide, 36mu16byfk, trifluroacetamide, trifluoro-acetamide, snylgqhjptadtaetp@, pubchem12622
• InChI Key: NRKYWOKHZRQRJR-UHFFFAOYSA-N
• IUPAC Name: 2,2,2-trifluoroacetamide
• PubChem CID: 67717
• Percent Purity: 97%

• Melting Point: 70°C to 75°C
• Molecular Formula: C2H2F3NO
• Beilstein: 1753625
• Solubility Information: Soluble in water (460g/L at 20°C),alcohol,ether,chloroform (partially),and methanol.
• SMILES: NC(=O)C(F)(F)F
• Molecular Weight (g/mol): 113.04
• Formula Weight: 113.04
• Chemical Name or Material: 2,2,2-Trifluoroacetamide

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

missing translation for 'einecsNumber' : 206-559-9

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only