2,5-Hexanedione, 97%, Thermo Scientific Chemicals

Description

2,5-Hexanedione is used as a reagent in the preparation of trans-2,5-dimethylpyrrolidine. It is also used in the synthesis of 2,5-dimethylpyrroles. Further, it plays an important role as a reagent used for the protection of amino groups in amino sugars and nucleosides. In addition to this, it is used in the preparation of five-membered heterocycles like indane-type and benzannulated systems. It is also employed as a precursor in Diels-alder cycloaddition reactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,5-Hexanedione is used as a reagent in the preparation of trans-2,5-dimethylpyrrolidine. It is also used in the synthesis of 2,5-dimethylpyrroles. Further, it plays an important role as a reagent used for the protection of amino groups in amino sugars and nucleosides. In addition to this, it is used in the preparation of five-membered heterocycles like indane-type and benzannulated systems. It is also employed as a precursor in Diels-alder cycloaddition reactions.

Solubility
Miscible with alcohol, water and diethyl ether.

Notes
Incompatible with strong oxidizing agents, strong bases, metals and strong reducing agents.

Specifications

Chemical Identifiers

• CAS: 110-13-4
• Molecular Formula: C6H10O2
• Molecular Weight (g/mol): 114.144
• MDL Number: MFCD00008792
• InChI Key: OJVAMHKKJGICOG-UHFFFAOYSA-N
• Synonym: 2,5-hexanedione, acetonylacetone, 1,2-diacetylethane, acetonyl acetone, diacetonyl, 2,5-diketohexane, 2,5-hexadione, acetone, acetonyl, 2,5-hexandione, alpha,beta-diacetylethane
• PubChem CID: 8035
• ChEBI: CHEBI:85014
• IUPAC Name: hexane-2,5-dione
• SMILES: CC(=O)CCC(=O)C

• Melting Point: -6°C
• Density: 0.976
• Boiling Point: 192°C to 193°C
• Flash Point: 78°C (172°F)
• Refractive Index: 1.425
• Quantity: 25 g
• Beilstein: 506525
• Merck Index: 14,71
• Solubility Information: Miscible with alcohol,water and diethyl ether.
• Formula Weight: 114.15
• Percent Purity: 97%
• Chemical Name or Material: 2,5-Hexanedione

Safety and Handling

Product Identifier

• 2,5-Hexanedione

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity after repeated exposure Category 2

Hazard Statement

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H373-May cause damage to organs.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Supplemental information

• MIXTURE LIST-Contains : 2,5-Hexanedione

RUO – Research Use Only