Thermo Scientific Chemicals 2'-Deoxycytidine

Description

2?-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2?-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2?-deoxyuridine. 2?-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2′-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. 2′-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK).

Solubility
Soluble in water, DMSO.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents. Stable under recommended storage conditions.

Specifications

Chemical Identifiers

• CAS: 951-77-9
• Molecular Formula: C9H13N3O4
• Molecular Weight (g/mol): 227.22
• MDL Number: MFCD00006547
• InChI Key: CKTSBUTUHBMZGZ-JORGKRSHNA-N
• Synonym: 2'-deoxycytidine, deoxycytidine, dcyd, cytosine deoxyriboside, cytidine, 2'-deoxy, deoxyribose cytidine, desoxycytidin german, 4-amino-1-2r,4s,5r-4-hydroxy-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one, cytosine, deoxyribonucleoside, d-cytidine
• PubChem CID: 13711
• ChEBI: CHEBI:15698
• IUPAC Name: 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• SMILES: NC1=NC(=O)N(C=C1)[C@H]1C[C@H](O)[C@@H](CO)O1

• Melting Point: 209°C to 211°C
• Color: White
• Quantity: 25 g
• Beilstein: 87567
• Solubility Information: Soluble in water,DMSO.
• Formula Weight: 227.22
• Physical Form: Crystalline Powder
• Chemical Name or Material: 2'-Deoxycytidine

RUO – Research Use Only