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Thermo Scientific Chemicals 2'-Deoxyguanosine monohydrate, 98+%
Description
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
Solubility
Soluble in NH4OH 1 M: 50 mg/mL, clear to very faintly turbid.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Specifications
Specifications
Color | White |
Quantity | 10 g |
Solubility Information | Soluble in NH4OH 1 M: 50mg/mL,clear to very faintly turbid. |
Formula Weight | 285.26 (267.25 Anhydrous) |
Physical Form | Crystalline Powder |
Chemical Name or Material | 2'-Deoxyguanosine |
Safety and Handling
- 2'-Deoxyguanosine monohydrate
- Warning
- Acute toxicity Category 4
- H302-Harmful if swallowed.
- P264-Wash face, hands and anyexposed skin thoroughly after handling.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
- MIXTURE LIST-Contains : 2'-Deoxyguanosine monohydrate
RUO – Research Use Only
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