2-Iminothiolane hydrochloride, Thermo Scientific Chemicals

Description

Protein modification and cross-linking reagent, cleavable by thiols

2-Iminothiolane hydrochloride is predominantly used as an amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides. It is also used as a RNA-protein crosslinking reagent as well as useful in cross-linking proteins..

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Iminothiolane hydrochloride is predominantly used as an amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides. It is also used as a RNA-protein crosslinking reagent as well as useful in cross-linking proteins..

Solubility
Freely soluble in water

Notes
Protect from moisture. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 4781-83-3
• Molecular Formula: C4H8ClNS
• Molecular Weight (g/mol): 137.625
• MDL Number: MFCD00039013
• InChI Key: ATGUDZODTABURZ-UHFFFAOYSA-N
• Synonym: 2-iminothiolane hydrochloride, 2-iminothiolane hcl, thiolan-2-imine hydrochloride, dihydrothiophen-2 3h-imine hydrochloride, 2 3h-thiophenimine, dihydro-, hydrochloride, traut's reagent, c4h7ns.clh, traut eo 1/4 a, 2-thiolanimine hydrochloride, 2 3h-thiophenimine, hydrochloride
• PubChem CID: 13166855
• IUPAC Name: thiolan-2-imine;hydrochloride
• SMILES: C1CC(=N)SC1.Cl

• Melting Point: 190°C to 195°C
• Color: White
• Quantity: 250 mg
• Beilstein: 3620079
• Solubility Information: Freely soluble in water
• Formula Weight: 137.63
• Physical Form: Powder
• Chemical Name or Material: 2-Iminothiolane hydrochloride

RUO – Research Use Only