Thermo Scientific™ 2'-OMe-U Phosphoramidite, standard grade, 28-400 finish bottle

2'-OMe-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-1825-11

Product Code. 17937192

Description

2'-OMe-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-uridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C₄₀H₅₆N₇O₉P
• Base: U
• Formula weight: 760.8 g/mol
• CAS number: 110764-79-9
• HPLC purity: ≥98.0%; Sum of non-primary peaks at 140-152ppm: ≤0.5%
• ³¹P NMR purity: ≥98.0%

Specifications

• For Use With (Equipment): MerMade Synthesizers
• Content And Storage: Store in freezer (at or below -20°C).
• Reagent Features: 2in-OMe modified
• Purity: 98%
• Reagent Type: Phosphoramidite
• Nucleic Acid Type: RNA

• Product Type: 2in-OMe-U CEP
• Nucleoside Type: Uridine (U)
• Shipping Condition: Room Temperature
• Quantity: 1 g
• Grade: Standard
• Form: Powder

For Research Use Only. Not for use in diagnostic procedures.