Tocris Bioscience™ VH 101 phenol-alkylC4-amine

VHL ligand with alkyl linker and terminal amine for onward chemistry

Brand:  Tocris Bioscience™ 7293/25

Product Code. 18749756

Description

VH 101 phenol-alkylC4-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

• Chemical Name or Material: (2 S,4 R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-(-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride
• Quantity: 25 mg
• Molecular Formula: C₃₀H₄₂FN₅O₅S0.2 HCl

• CAS: 2564467-03-2
• Target: Degrader Building Blocks
• Purity: 0.95