3,4-Dichloroisocoumarin, 98%, Thermo Scientific Chemicals

Description

 

Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymotrypsin and Trypsin. ,4 Dichloroisocoumarin also inhibits granzymes A, B, and H, cathepsin G, neutrophil elastase, proteinase and blocks apoptotic internucleosomal DNA cleavage in thymocytes without the involvement of endonucleases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors. It is an inhibitor of Chymot

Specifications

• CAS: 51050-59-0
• Color: White
• Molecular Formula: C9H4Cl2O2
• MDL Number: MFCD00036960
• Quantity: 10 mg
• UN Number: UN2811
• Beilstein: 6802625
• Synonym: 3,4-dichloroisocoumarin, 3,4-dcl, 1h-2-benzopyran-1-one,3,4-dichloro, 3,4-dci, 3,4 dichloroisocoumarin, 3,4-dichloro-1h-isochromen-1-one, 3,4-dichloro-1h-2-benzopyran-1-one, 1h-2-benzopyran-1-one, 3,4-dichloro, chembl24983, 3,4-dichloro-2-benzopyran-1-one
• Solubility Information: Soluble in DMF or DMSO at a concentration of 10mM
• InChI Key: SUGXUUGGLDCZKB-UHFFFAOYSA-N
• SMILES: ClC1=C(Cl)C2=CC=CC=C2C(=O)O1
• IUPAC Name: 3,4-dichloroisochromen-1-one
• Molecular Weight (g/mol): 215.03
• PubChem CID: 1609
• Formula Weight: 215.03
• Percent Purity: 99%
• Physical Form: Powder
• Chemical Name or Material: 3,4-Dichloroisocoumarin

RUO – Research Use Only