3,5-Di-tert-butyl-2-hydroxybenzaldehyde, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11440308	Thermo Scientific Alfa Aesar B23834.06	5 g
11450308	Thermo Scientific Alfa Aesar B23834.14	25 g
11460308	Thermo Scientific Alfa Aesar B23834.22	100 g

Description

3,5-Di-tert-butyl-2-hydroxybenzaldehyde is used in the synthesis of Mn(III)-salen complex and its diamino precursor 5,6-diamino-5,6-dideoxy-1,2-O-isopropylidene-3-O-methyl-β-L-idofuranose, chiral Schiff base ligand for an enantioselective copper-catalyzed addition of phenyl acetylene to imines, chiral oxazolidine ligand for the enantioselective addition of diethyl zinc to aldehydes and tin Schiff base complexes with histidine analogues. It has antibacterial activity and is used in the preparation nickel complexes. It is structurally related to 3,5-di-t-butylcatechol (DTCAT) but is not as potent an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3,5-Di-tert-butyl-2-hydroxybenzaldehyde is used in the synthesis of Mn(III)-salen complex and its diamino precursor 5,6-diamino-5,6-dideoxy-1,2-O-isopropylidene-3-O-methyl-β-L-idofuranose, chiral Schiff base ligand for an enantioselective copper-catalyzed addition of phenyl acetylene to imines, chiral oxazolidine ligand for the enantioselective addition of diethyl zinc to aldehydes and tin Schiff base complexes with histidine analogues. It has antibacterial activity and is used in the preparation nickel complexes. It is structurally related to 3,5-di-t-butylcatechol (DTCAT) but is not as potent an activator of rat skeletal muscle ryanodine receptor Ca2+ channel (RyRC).

Solubility
Soluble in DMSO and methanol.

Notes
Air sensitive. Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Chemical Identifiers

• CAS: 37942-07-7
• Molecular Weight (g/mol): 234.339
• InChI Key: RRIQVLZDOZPJTH-UHFFFAOYSA-N
• PubChem CID: 688023
• SMILES: CC(C)(C)C1=CC(=C(C(=C1)C=O)O)C(C)(C)C

• Molecular Formula: C15H22O2
• MDL Number: MFCD00191998
• Synonym: 3,5-di-tert-butyl-2-hydroxybenzaldehyde, 3,5-di-tert-butylsalicylaldehyde, 3,5-bis 1,1-dimethylethyl-2-hydroxy-benzaldehyde, benzaldehyde, 3,5-bis 1,1-dimethylethyl-2-hydroxy, 3,5-di-t-butylsalicylaldehyde, 3,5-di-tert-butyl-2-hydroxy-benzaldehyde, benzaldehyde, 2-hydroxy, 3,5-di t-butyl, 3,5-bis tert-butyl-2-hydroxybenzaldehyde, pubchem11247, acmc-1aeteShow MoreShow Less
• IUPAC Name: 3,5-ditert-butyl-2-hydroxybenzaldehyde

Specifications

• CAS: 37942-07-7
• Assay Percent Range: 0.99
• MDL Number: MFCD00191998
• Sensitivity: Air Sensitive
• Solubility Information: Soluble in DMSO and methanol.
• SMILES: CC(C)(C)C1=CC(=C(C(=C1)C=O)O)C(C)(C)C
• Molecular Weight (g/mol): 234.339
• Formula Weight: 234.34
• Chemical Name or Material: 3,5-Di-tert-butyl-2-hydroxybenzaldehyde

• Melting Point: 59°C to 61°C
• Molecular Formula: C15H22O2
• Beilstein: 1877810
• Synonym: 3,5-di-tert-butyl-2-hydroxybenzaldehyde, 3,5-di-tert-butylsalicylaldehyde, 3,5-bis 1,1-dimethylethyl-2-hydroxy-benzaldehyde, benzaldehyde, 3,5-bis 1,1-dimethylethyl-2-hydroxy, 3,5-di-t-butylsalicylaldehyde, 3,5-di-tert-butyl-2-hydroxy-benzaldehyde, benzaldehyde, 2-hydroxy, 3,5-di t-butyl, 3,5-bis tert-butyl-2-hydroxybenzaldehyde, pubchem11247, acmc-1aete
• InChI Key: RRIQVLZDOZPJTH-UHFFFAOYSA-N
• IUPAC Name: 3,5-ditert-butyl-2-hydroxybenzaldehyde
• PubChem CID: 688023
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

missing translation for 'einecsNumber' : 000-000-0

missing translation for 'tsca' : No

missing translation for 'storageNote' : Air Sensitive

Recommended Storage : Ambient temperatures

RUO – Research Use Only