3-Bromo-1-trimethylsilyl-1-propyne, 98%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
15430278	Thermo Scientific Alfa Aesar H53451.06	5 g
15440278	Thermo Scientific Alfa Aesar H53451.14	25 g

Description

3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.

Solubility
Immiscible with water.

Notes
Store in cool place. Incompatible with strong oxidizing agents.

Chemical Identifiers

• CAS: 38002-45-8
• Molecular Weight (g/mol): 191.143
• InChI Key: GAPRPFRDVCCCHR-UHFFFAOYSA-N
• PubChem CID: 642589
• SMILES: C[Si](C)(C)C#CCBr

• Molecular Formula: C6H11BrSi
• MDL Number: MFCD00134460
• Synonym: 3-bromo-1-trimethylsilyl-1-propyne, 3-bromoprop-1-yn-1-yl trimethylsilane, 3-bromo-1-propynyl trimethylsilane, 3-trimethylsilyl propargyl bromide, 3-bromoprop-1-ynyl trimethyl silane, silane, 3-bromo-1-propynyl trimethyl, 3-bromoprop-1-yn-1-yl trimethyl silane, acmc-1cthe, ksc496i3r
• IUPAC Name: 3-bromoprop-1-ynyl(trimethyl)silane

Specifications

• Boiling Point: 44°C to 45°C (2mmHg)
• Molecular Formula: C6H11BrSi
• MDL Number: MFCD00134460
• Flash Point: 63°C (145°F)
• Solubility Information: Immiscible with water.
• SMILES: C[Si](C)(C)C#CCBr
• Molecular Weight (g/mol): 191.143
• Formula Weight: 191.14
• Refractive Index: 1.483
• Chemical Name or Material: 3-Bromo-1-trimethylsilyl-1-propyne

• CAS: 38002-45-8
• Linear Formula: BrCH₂C≡CSi(CH₃)₃
• Beilstein: 2037650
• Synonym: 3-bromo-1-trimethylsilyl-1-propyne, 3-bromoprop-1-yn-1-yl trimethylsilane, 3-bromo-1-propynyl trimethylsilane, 3-trimethylsilyl propargyl bromide, 3-bromoprop-1-ynyl trimethyl silane, silane, 3-bromo-1-propynyl trimethyl, 3-bromoprop-1-yn-1-yl trimethyl silane, acmc-1cthe, ksc496i3r
• InChI Key: GAPRPFRDVCCCHR-UHFFFAOYSA-N
• IUPAC Name: 3-bromoprop-1-ynyl(trimethyl)silane
• PubChem CID: 642589
• Percent Purity: 98%
• Density: 1.17

Safety and Handling

GHS H Statement
H315-H319-H335-H227
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Combustible liquid.

P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P370+P378q-P501c

H227-H315-H319-H335

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures

RUO – Research Use Only