3-Bromopyridine, 98+%, Thermo Scientific Chemicals

Description

3-Bromopyridine undergoes lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Bromopyridine undergoes lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines.

Solubility
Soluble in water (31 g/L at 20°C).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Incompatible with strong acids.

Specifications

Chemical Identifiers

• CAS: 626-55-1
• Molecular Formula: C5H4BrN
• Molecular Weight (g/mol): 158.00
• MDL Number: MFCD00006373
• InChI Key: NYPYPOZNGOXYSU-UHFFFAOYSA-N
• Synonym: 3-pyridyl bromide, pyridine, 3-bromo, 3-bromo pyridine, 3-bromo-pyridine, 5-bromopyridine, unii-xmn8h2xe9h, 5-bromo pyridine, xmn8h2xe9h, 3-pyridylbromide, 3-bromopryidine
• PubChem CID: 12286
• ChEBI: CHEBI:51575
• IUPAC Name: 3-bromopyridine
• SMILES: BrC1=CC=CN=C1

• Melting Point: -27°C
• Density: 1.617
• Boiling Point: 172°C to 174°C
• Flash Point: 72°C (181°F)
• Odor: Characteristic
• Refractive Index: 1.57
• Quantity: 100 g
• UN Number: UN2810
• Beilstein: 105880
• Solubility Information: Soluble in water (31g/L at 20°C).
• Formula Weight: 158
• Percent Purity: ≥98%
• Chemical Name or Material: 3-Bromopyridine

RUO – Research Use Only