3-Bromopyridine, 98+%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11495333	Thermo Scientific Alfa Aesar A12894.14	25 g
11405343	Thermo Scientific Alfa Aesar A12894.22	100 g
11415343	Thermo Scientific Alfa Aesar A12894.36	500 g

Description

3-Bromopyridine undergoes lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Bromopyridine undergoes lithiation with LDA at low temperatures in the 4-position: Heterocycles, involved in formation of the Grignard by Mg exchange with i-PrMgCl and in transmetallation of the lithiated derivative with zinc chloride followed by treatment with an electrophile as a route to 4-substituted 3-bromopyridines.

Solubility
Soluble in water (31 g/L at 20°C).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Incompatible with strong acids.

Chemical Identifiers

• CAS: 626-55-1
• Molecular Weight (g/mol): 158.00
• InChI Key: NYPYPOZNGOXYSU-UHFFFAOYSA-N
• PubChem CID: 12286
• IUPAC Name: 3-bromopyridine

• Molecular Formula: C5H4BrN
• MDL Number: MFCD00006373
• Synonym: 3-pyridyl bromide, pyridine, 3-bromo, 3-bromo pyridine, 3-bromo-pyridine, 5-bromopyridine, unii-xmn8h2xe9h, 5-bromo pyridine, xmn8h2xe9h, 3-pyridylbromide, 3-bromopryidine
• ChEBI: CHEBI:51575
• SMILES: BrC1=CC=CN=C1

Specifications

• CAS: 626-55-1
• Density: 1.617
• Flash Point: 72°C (181°F)
• Molecular Formula: C5H4BrN
• MDL Number: MFCD00006373
• Beilstein: 105880
• Solubility Information: Soluble in water (31g/L at 20°C).
• SMILES: BrC1=CC=CN=C1
• Molecular Weight (g/mol): 158.00
• ChEBI: CHEBI:51575
• Percent Purity: ≥98%

• Melting Point: -27°C
• Boiling Point: 172°C to 174°C
• Odor: Characteristic
• Refractive Index: 1.57
• UN Number: UN2810
• Synonym: 3-pyridyl bromide, pyridine, 3-bromo, 3-bromo pyridine, 3-bromo-pyridine, 5-bromopyridine, unii-xmn8h2xe9h, 5-bromo pyridine, xmn8h2xe9h, 3-pyridylbromide, 3-bromopryidine
• InChI Key: NYPYPOZNGOXYSU-UHFFFAOYSA-N
• IUPAC Name: 3-bromopyridine
• PubChem CID: 12286
• Formula Weight: 158
• Chemical Name or Material: 3-Bromopyridine

Safety and Handling

GHS H Statement
H311-H227-H302-H332-H315-H319-H335
Toxic in contact with skin.
Combustible liquid.
Harmful if swallowed.
Harmful if inhaled.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P311-P312-P330-P332+P313-P363-P370+P378q-P501c

H226-H301+H311+H331-H315-H319-H335

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missing translation for 'einecsNumber' : 210-952-0

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only