3-Chloropropanesulfonyl chloride, 98+%, Thermo Scientific Chemicals

Description

3-Chloropropanesulfonyl Chloride is an intermediate used in the preparation of many enzymatic inhibitors. It is also used in the generation and trapping of the derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids provide chiral sultams and sultones. It is mainly used for the synthesis of pharmaceutical intermediates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Chloropropanesulfonyl Chloride is an intermediate used in the preparation of many enzymatic inhibitors. It is also used in the generation and trapping of the derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids provide chiral sultams and sultones. It is mainly used for the synthesis of pharmaceutical intermediates.

Solubility
Soluble in dichloromethane, ethyl Acetate and hexane.

Notes
Store at -20°C. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Moisture sensitive. Keep away from alcohols, strong bases, oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1633-82-5
• Molecular Formula: C3H6Cl2O2S
• Molecular Weight (g/mol): 177.039
• MDL Number: MFCD00007463
• InChI Key: GPKDGVXBXQTHRY-UHFFFAOYSA-N
• Synonym: 3-chloropropanesulfonyl chloride, 3-chloro-1-propanesulfonyl chloride, 3-chloropropanesulfonylchloride, 3-chloropropylsulfonyl chloride, 3-chloropropanesulphonyl chloride, 1-propanesulfonyl chloride, 3-chloro, propanesulfonyl chloride, chloro, 3-chloro-propane-1-sulfonyl chloride, gamma-chloropropanesulfonyl chloride, 3-chloropropylsulfonylchloride
• PubChem CID: 15410
• IUPAC Name: 3-chloropropane-1-sulfonyl chloride
• SMILES: C(CS(=O)(=O)Cl)CCl

• Density: 1.456
• Boiling Point: 70°C (0.5 mmHg)
• Flash Point: >110°C (230°F)
• Linear Formula: Cl(CH₂)₃SO₂Cl
• Refractive Index: 1.49
• Quantity: 10 g
• UN Number: UN3265
• Beilstein: 1754119
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in dichloromethane,ethyl Acetate and hexane.
• Formula Weight: 177.05
• Percent Purity: ≥98%
• Chemical Name or Material: 3-Chloropropanesulfonyl chloride

Safety and Handling

Product Identifier

• 3-Chloropropanesulfonyl chloride

Signal Word

• Danger

Hazard Category

• Serious eye damage/eye irritation Category 1
• Skin corrosion/irritation Category 1 B

Hazard Statement

• H314-Causes severe skin burns and eye damage.
• H318-Causes serious eye damage.
• EUH029-Contact with water liberates toxic gas.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P310-Immediately call a POISON CENTER/doctor/.
• P402+P404-Store in a dry place. Store in a closed container.

Supplemental information

• MIXTURE LIST-Contains : 3-Chloropropanesulphonyl chloride

RUO – Research Use Only