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3-Isobutyl-1-methylxanthine, Thermo Scientific Chemicals
Description
3-Isobutyl-1-methylxanthine is used in inhibition of phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50 = 1.3 uM). Also inhibits ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. Inhibits the growth of carcinoma cells.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
3-Isobutyl-1-methylxanthine is used in inhibition of phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50 = 1.3 uM). Also inhibits ion channels in the neuromuscular junction.
Specifications
Specifications
CAS | 28822-58-4 |
Melting Point | 200°C to 201°C |
Molecular Formula | C10H14N4O2 |
MDL Number | MFCD00005584 |
Quantity | 100 mg |
Synonym | 3-isobutyl-1-methylxanthine, ibmx, isobutylmethylxanthine, 1-methyl-3-isobutylxanthine, methylisobutylxanthine, 3-isobutyl-1-methyl-1h-purine-2,6 3h,7h-dione, xanthine, 3-isobutyl-1-methyl, 3-isobutyl-1-methyxanthine, 1h-purine-2,6-dione, 3,7-dihydro-1-methyl-3-2-methylpropyl, methyl-isobutylxanthine |
Solubility Information | Soluble in ethanol. |
InChI Key | APIXJSLKIYYUKG-UHFFFAOYSA-N |
SMILES | CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O |
IUPAC Name | 1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione |
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Safety and Handling
- 3-Isobutyl-1-methylxanthine
- Warning
- Acute toxicity Category 4
- H302-Harmful if swallowed.
- P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
- MIXTURE LIST-Contains : 3,7-Dihydro-3-isobutyl-1-methyl-1H-purine2,6-dione
RUO – Research Use Only
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