3-Maleimidopropionic acid N-hydroxysuccinimide ester, 99%, Thermo Scientific Chemicals

Description

3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.

Solubility
Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat, water, moisture.

Specifications

Chemical Identifiers

• CAS: 55750-62-4
• Molecular Formula: C11H10N2O6
• Molecular Weight (g/mol): 266.209
• MDL Number: MFCD00043141
• InChI Key: JKHVDAUOODACDU-UHFFFAOYSA-N
• Synonym: n-succinimidyl 3-maleimidopropionate, 2,5-dioxopyrrolidin-1-yl 3-2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl propanoate, 3-maleimido propionic acid n-hydroxysuccinimide ester, bmps, 3-maleimidopropionic acid n-succinimidyl ester, 3-maleimidopropionic acid nhs, succinimido 3-maleimidopropanoate, 2,5-dioxopyrrolidin-1-yl 3-2,5-dioxopyrrol-1-yl propanoate, 3-maleimidopropionic acid n-hydroxysuccinimide ester
• PubChem CID: 4620597
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate
• SMILES: C1CC(=O)N(C1=O)OC(=O)CCN2C(=O)C=CC2=O

• Melting Point: 168°C to 170°C
• Quantity: 250 mg
• Sensitivity: Moisture sensitive
• Solubility Information: Insoluble in water.
• Formula Weight: 266.21
• Percent Purity: 99%
• Chemical Name or Material: 3-Maleimidopropionic acid N-hydroxysuccinimide ester

Safety and Handling

Product Identifier

• 3-Maleimidopropionic acid N-hydroxysuccinimide ester

Signal Word

• Warning

Hazard Category

• Specific target organ toxicity Category 3

Hazard Statement

• H335-May cause respiratory irritation.

Precautionary Statement

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : 3-Maleimidopropionicacid N-hydroxysuccinimide ester

RUO – Research Use Only