3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, 97+%, Thermo Scientific Chemicals

Description

3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt is a cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt is a cross-linking reagent incorporating an extended spacer with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

Solubility
Soluble in water (2.5 mg/ml) and dimethyl formamide.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 92921-24-9
• Molecular Formula: C16H17N2NaO9S
• Molecular Weight (g/mol): 436.367
• MDL Number: MFCD00054978
• InChI Key: VUFNRPJNRFOTGK-UHFFFAOYSA-M
• Synonym: sulfo-smcc, sodium 1-4-2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl methyl cyclohexanecarbonyl oxy-2,5-dioxopyrrolidine-3-sulfonate, sulfo-smcc sodium, 4-maleimidomethyl cyclohexane-1-carboxylic acid 3-sulfo-n-hydroxysuccinimide ester sodium salt, 3-sulfo-n-succinimidyl 4-n-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-trans-smcc, sulfo-smcc crosslinker, sulfo-n-succinimidyl 4-maleimidomethyl cyclohexane-1-carboxylate sodium salt, sulfo-smcc sodium salt, bicl207
• PubChem CID: 4618794
• IUPAC Name: sodium;1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
• SMILES: C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]

• Quantity: 25 mg
• Solubility Information: Soluble in water (2.5mg/ml) and dimethyl formamide.
• Formula Weight: 436.37
• Percent Purity: ≥98%
• Chemical Name or Material: 3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt

RUO – Research Use Only