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4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, 97%, Thermo Scientific Chemicals
Description
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
AEBSF is extensively used in studies aiming to describe cholesterol regulatory genes due to its potent ability to inhibit Site-1-protease (S1P). This serine protease, located in the Golgi apparatus, is responsible for activating the sterol regulatory element-binding proteins. By selectively inhibiting S1P, AEBSF can be used to characterize the downstream result of SREBP inhibition and its influence on cholesterol regulation.
Solubility
Soluble in water 50 mg/mL or 100% ethanol.
Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air, moisture.
Specifications
Specifications
Melting Point | ∼184°C (decomposition) |
Quantity | 1 g |
UN Number | UN3261 |
Beilstein | 7604627 |
Sensitivity | Moisture sensitive |
Solubility Information | Soluble in water 50mg/mL or 100% ethanol. |
Formula Weight | 239.69 |
Percent Purity | 97% |
Chemical Name or Material | 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride |
Safety and Handling
- 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
- Danger
- Serious eye damage/eye irritation Category 1
- Skin corrosion/irritation Category 1 B
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : 4-(2-Aminoethyl)benzenesulfonyl fluoridehydrochloride
RUO – Research Use Only
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