4-Acetylpyridine, 98%, Thermo Scientific Chemicals

Description

4-acetylpyridine on reaction with - and 4-formylpyridine (H3FoPyS, H4FoPyS) yields semicarbazones. Reaction of acetylpyridine with thiophene-2-carboxaldehyde afforded the 2-chloro-6-ethoxy-4-β-(2-thienyl)acryloylpyridine, which was reacted with malononitrile in refluxing ethanol in the presence of piperidine as a catalyst to afford the cyanoaminopyrane derivative.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-acetylpyridine on reaction with - and 4-formylpyridine (H3FoPyS, H4FoPyS) yields semicarbazones. Reaction of acetylpyridine with thiophene-2-carboxaldehyde afforded the 2-chloro-6-ethoxy-4-β-(2-thienyl)acryloylpyridine, which was reacted with malononitrile in refluxing ethanol in the presence of piperidine as a catalyst to afford the cyanoaminopyrane derivative.

Solubility
Insoluble in water. Soluble in alcohol.

Notes
Store in cool place. Keep away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1122-54-9
• Molecular Formula: C7H7NO
• Molecular Weight (g/mol): 121.139
• MDL Number: MFCD00006433
• InChI Key: WMQUKDQWMMOHSA-UHFFFAOYSA-N
• Synonym: 4-acetylpyridine, methyl 4-pyridyl ketone, ethanone, 1-4-pyridinyl, ketone, methyl 4-pyridyl, 1-pyridin-4-yl ethan-1-one, 1-pyridin-4-yl ethanone, pyridine, 4-acetyl, 4-acetyl pyridine, 4-pyridyl methyl ketone, unii-g47437iow7
• PubChem CID: 14282
• IUPAC Name: 1-pyridin-4-ylethanone
• SMILES: CC(=O)C1=CC=NC=C1

• Melting Point: 14°C to 16°C
• Density: 1.103
• Boiling Point: 210°C to 212°C
• Flash Point: 104°C (219°F)
• Refractive Index: 1.535
• Quantity: 25 g
• Beilstein: 107629
• Solubility Information: Insoluble in water. Soluble in alcohol.
• Formula Weight: 121.14
• Percent Purity: 98%
• Chemical Name or Material: 4-Acetylpyridine

RUO – Research Use Only