4-(Boc-amino)-2-fluorobenzeneboronic acid pinacol ester, 96%, Thermo Scientific™

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
It is the key intermediate in the synthesis of ,3-Dihydro-1,4-benzodiazepin-2(2H)-ones and 3-Amino-1,3-dihydro-1,4-benzodiazepin-2(2H)-ones. This synthesis is done with Pd-catalyzed cross-coupling of imidoyl chlorides with organoboronic acids.

Notes
Store at room temperature. Keep away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1256256-45-7
• Molecular Formula: C17H25BFNO4
• Molecular Weight (g/mol): 337.198
• MDL Number: MFCD18383441
• InChI Key: FALNYBWTRBHWID-UHFFFAOYSA-N
• Synonym: tert-butyl 3-fluoro-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl phenyl carbamate, tert-butyl n-3-fluoro-4-4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl phenyl carbamate, 4-boc-amino-2-fluorobenzeneboronic acid pinacol ester, 3-fluoro-4-4,4,5,5-tetramethyl 1,3,2 dioxaborolan-2-yl phenyl carbamic acid tert-butyl ester
• PubChem CID: 59578631
• IUPAC Name: tert-butyl N-[3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate
• SMILES: B1(OC(C(O1)(C)C)(C)C)C2=C(C=C(C=C2)NC(=O)OC(C)(C)C)F

• Melting Point: 150°C to 152°C
• Quantity: 250 mg
• Formula Weight: 337.2
• Percent Purity: 96%
• Chemical Name or Material: 4-(Boc-amino)-2-fluorobenzeneboronic acid pinacol ester