4-Isobutyl-alpha-methylphenylacetic acid, 99%, Thermo Scientific Chemicals

Description

Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ibuprofen is useful as a nonsteroidal anti-inflammatory research chemical. Ibuprofen is reported to inhibit the netrophil-dependent edema response of rabbit skin to C5a/PGE23. NSAID that inhibits cyclooxygenase-1 and -2.

Solubility
Insoluble in water. Soluble in ethanol (25 mg/ml), chloroform (1:1), ether (1:2), acetone (1:1.5), aqueous solutions of alkali hydroxides and carbonates, dichloromethane, methanol (50 mg/ml), and ethyl acetate.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 15687-27-1
• Molecular Formula: C13H18O2
• Molecular Weight (g/mol): 206.29
• MDL Number: MFCD00010393
• InChI Key: HEFNNWSXXWATRW-UHFFFAOYNA-N
• Synonym: ibuprofen, 2-4-isobutylphenyl propanoic acid, motrin, brufen, nurofen, advil, dolgit, liptan, nuprin, anflagen
• PubChem CID: 3672
• ChEBI: CHEBI:5855
• IUPAC Name: 2-[4-(2-methylpropyl)phenyl]propanoic acid
• SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(O)=O

• Melting Point: 75°C to 78°C
• Boiling Point: 157°C (4 mmHg)
• Odor: Odorless
• Quantity: 1 g
• UN Number: UN3077
• Merck Index: 14,4881
• Solubility Information: Insoluble in water. Soluble in ethanol (25mg/ml),chloroform (1:1),ether (1:2),acetone (1:1.5),aqueous solutions of alkali hydroxides and carbonates,dichloromethane,methanol (50mg/ml),and ethyl acetate.
• Formula Weight: 206.29
• Percent Purity: 99%
• Chemical Name or Material: 4-Isobutyl-alpha-methylphenylacetic acid

Safety and Handling

Product Identifier

• 4-Isobutyl-alpha-methylphenylacetic acid

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : 4-Isobutyl-alpha-methylphenylacetic acid

RUO – Research Use Only