4-Nitrophenol, 99%, Thermo Scientific Chemicals

Description

4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is used as an intermediate in the synthesis of paracetamol and N-acetyl-p-aminophenol dyestuffs.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is used as an intermediate in the synthesis of paracetamol and N-acetyl-p-aminophenol dyestuffs.

Solubility
Freely soluble in alcohol, chloroform, ether. Freely soluble in acetone. Slightly soluble in water.

Notes
Incompatible with strong oxidizing agents and strong bases.

Specifications

Chemical Identifiers

• CAS: 100-02-7
• Molecular Formula: C6H5NO3
• Molecular Weight (g/mol): 139.11
• MDL Number: MFCD00007331
• InChI Key: BTJIUGUIPKRLHP-UHFFFAOYSA-N
• Synonym: p-nitrophenol, phenol, 4-nitro, paranitrophenol, niphen, 4-hydroxynitrobenzene, p-hydroxynitrobenzene, phenol, p-nitro, mononitrophenol, paranitrofenol, paranitrofenolo
• PubChem CID: 980
• ChEBI: CHEBI:16836
• IUPAC Name: 4-nitrophenol
• SMILES: OC1=CC=C(C=C1)[N+]([O-])=O

• Melting Point: 110°C to 115°C
• Density: 1.48
• Boiling Point: 279°C (decomposition)
• Flash Point: 169°C (336°F)
• Quantity: 250 g
• UN Number: UN1663
• Beilstein: 1281877
• Sensitivity: Light sensitive
• Merck Index: 14,6621
• Solubility Information: Freely soluble in alcohol,chloroform,ether; Freely soluble in acetone; Slightly soluble in water.
• Formula Weight: 139.11
• Percent Purity: 99%
• Chemical Name or Material: 4-Nitrophenol

Safety and Handling

Product Identifier

• 4-Nitrophenol

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Acute toxicity Category 4
• Specific target organ toxicity after repeated exposure Category 2

Hazard Statement

• H301-Toxic if swallowed.
• H312-Harmful in contact with skin.
• H332-Harmful if inhaled.
• H373-May cause damage to organs.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.

Supplemental information

• MIXTURE LIST-Contains : p-Nitrophenol

RUO – Research Use Only