4-Trifluoromethyl-1H-pyrazole, 97%, Thermo Scientific Chemicals

Description

It is used as pharmaceutical intermediates. The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as pharmaceutical intermediates. The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles.

Notes
Incompatible with strong oxidizing agents. Store at room temperature.

Specifications

Chemical Identifiers

• CAS: 52222-73-8
• Molecular Formula: C4H3F3N2
• Molecular Weight (g/mol): 136.077
• MDL Number: MFCD11226572
• InChI Key: KDEJQUNODYXYBJ-UHFFFAOYSA-N
• Synonym: 4-trifluoromethyl-1h-pyrazole, 1h-pyrazole, 4-trifluoromethyl, 4-trifluoromethylpyrazole, 4-trifluoromethyl pyrazole, 4-trifluoromethyl-1 h-pyrazole, 4-trifluoromethyl ;-1h-pyrazole
• PubChem CID: 12777795
• IUPAC Name: 4-(trifluoromethyl)-1H-pyrazole
• SMILES: C1=C(C=NN1)C(F)(F)F

• Melting Point: 76°C to 78°C
• Quantity: 1 g
• Formula Weight: 136.1
• Percent Purity: 97%
• Chemical Name or Material: 4-Trifluoromethyl-1H-pyrazole

RUO – Research Use Only