4-(Trifluoromethyl)benzeneboronic acid, 98%, Thermo Scientific Chemicals

Description

4-(Trifluoromethyl)benzeneboronic acid is used of this drug is to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-(Trifluoromethyl)benzeneboronic acid is used of this drug is to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.

Solubility
Soluble in DMSO, not in water

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Specifications

Chemical Identifiers

• CAS: 128796-39-4
• Molecular Formula: C7H6BF3O2
• Molecular Weight (g/mol): 189.93
• MDL Number: MFCD00151855
• InChI Key: ALMFIOZYDASRRC-UHFFFAOYSA-N
• Synonym: 4-trifluoromethyl phenylboronic acid, 4-trifluoromethylphenylboronic acid, 4-trifluoromethyl benzeneboronic acid, 4-trifluoromethyl phenyl boronic acid, 4-trifluoromethylphenyl boronic acid, 4-trifluoromethyl phenyl boranediol, 4-boronobenzotrifluoride, p-trifluoromethyl phenylboronic acid, 4-trifluoromethylphenyl-boronic acid
• PubChem CID: 2734389
• IUPAC Name: [4-(trifluoromethyl)phenyl]boronic acid
• SMILES: OB(O)C1=CC=C(C=C1)C(F)(F)F

• Melting Point: 238°C to 242°C
• Quantity: 1 g
• Beilstein: 3544189
• Solubility Information: Soluble in DMSO,not in water
• Formula Weight: 189.93
• Percent Purity: 98%
• Chemical Name or Material: 4-(Trifluoromethyl)benzeneboronic acid

Safety and Handling

Product Identifier

• 4-(Trifluoromethyl)benzeneboronic acid

Signal Word

• Warning

Hazard Category

• Acute toxicity Category 4
• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Hazard Statement

• H302-Harmful if swallowed.
• H312-Harmful in contact with skin.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H332-Harmful if inhaled.
• H335-May cause respiratory irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : 4-(Trifluoromethyl)benzeneboronic acid

RUO – Research Use Only