4EBP1 Monoclonal Antibody (9E12D9), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515312

Product Code. 11315293

Description

MA5-15312 targets 4E-BP1 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15312 immunogen is purified recombinant fragment of 4EBP1 expressed in E. Coli.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Specifications

• Antigen: 4EBP1
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: Q13541
• Gene Symbols: EIF4EBP1
• Immunogen: Purified recombinant fragment of 4EBP1 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 1978
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 9E12D9
• Conjugate: Unconjugated
• Gene: EIF4EBP1
• Gene Alias: 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1