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5,7-Dihydroxy-4'-methoxyisoflavone, 98%, Thermo Scientific Chemicals
£53.30 - £685.00
Chemical Identifiers
CAS | 491-80-5 |
---|---|
Molecular Formula | C16H12O5 |
Molecular Weight (g/mol) | 284.27 |
MDL Number | MFCD00006839 |
InChI Key | WUADCCWRTIWANL-UHFFFAOYSA-N |
Synonym | biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl |
PubChem CID | 5280373 |
ChEBI | CHEBI:17574 |
IUPAC Name | 5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one |
SMILES | COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
11310528
|
Thermo Scientific Alfa Aesar
043853.MD |
250 mg |
£53.30
250mg |
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11320528
|
Thermo Scientific Alfa Aesar
043853.03 |
1 g |
£168.00
1g |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
11330528
|
Thermo Scientific Alfa Aesar
043853.06 |
5 g |
£685.00
5g |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
It has putative benefits in dietary cancer prophylaxis. It has also been found to inhibit fatty acid amide hydrolase and to act as agonist of PPARgamma, nuclear receptor that is current pharmacological target for the treatment of diabetes type 2. It acts as an antineoplastic agent. It is a selective agonist at ER-β estrogen receptors, and may have chemopreventive efficacy against breast cancer. In line with its low activity at ER-α estrogen receptors, it is essentially devoid of uterotrophic activity. Biochanin A is also a ligand for the aryl hydrocarbon receptor (AhR). It reduces arterial resistance and enhances microcirculation perhaps via effects on potassium and/or calcium ion channels. Induction of sulfotransferases for xenobiotic detoxification has been proposed as a mechanism of its cancer preventive effects. It is a nitric oxide synthase inhibitor and apoptosis inducer
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Chemical Identifiers
491-80-5 | |
284.27 | |
WUADCCWRTIWANL-UHFFFAOYSA-N | |
5280373 | |
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one |
C16H12O5 | |
MFCD00006839 | |
biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl | |
CHEBI:17574 | |
COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O |
Specifications
491-80-5 | |
C16H12O5 | |
278107 | |
Soluble in water (<1mg/ml at 25°C),chloroform,methanol,DMSO (57mg/ml at 25°C),and ethanol (9mg/ml at 25°C). | |
COC1=CC=C(C=C1)C1=COC2=CC(O)=CC(O)=C2C1=O | |
284.27 | |
CHEBI:17574 | |
98% | |
5,7-Dihydroxy-4'-methoxyisoflavone |
210°C to 213°C | |
MFCD00006839 | |
biochanin a, biochanin, 4'-methylgenistein, 5,7-dihydroxy-4'-methoxyisoflavone, 5,7-dihydroxy-3-4-methoxyphenyl-4h-chromen-4-one, genistein 4-methyl ether, pratensol, biochanine a, 5,7-dihydrox-4'-methoxyisoflavone, 4h-1-benzopyran-4-one, 5,7-dihydroxy-3-4-methoxyphenyl | |
WUADCCWRTIWANL-UHFFFAOYSA-N | |
5,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one | |
5280373 | |
284.27 | |
Powder |
Safety and Handling
missing translation for 'einecsNumber' : 207-744-7
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures
RUO – Research Use Only