Tocris Bioscience™ 5J 4

CRAC channel blocker; anti-inflammatory

Brand:  Tocris Bioscience™ 5490/10

Product Code. 18766597

Description

5J 4 is a calcium release-activated calcium (CRAC) channel blocker. Blocks store-operated calcium entry (SOCE) in HeLa-O+S cells and Th17 cells in vitro. Ameliorates symptoms and reduces CNS infiltration by mononuclear cells in a mouse model of experimental autoimmune encephalomyelitis (EAE) in vivo.

Specifications

• Chemical Name or Material: N-[[(6-Hydroxy-1-naphthalenyl)amino]thioxomethyl]-2-furancarboxamide
• Quantity: 10 mg
• Molecular Formula: C₁₆H₁₂N₂O₃S
• Purity: >98%

• CAS: 827001-82-1
• Target: Other Calcium Channel Blockers
• Formula Weight: 312.34