6-Mercaptopurine monohydrate, 98%, Thermo Scientific Chemicals

Description

6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
6-Mercaptopurine is a widely used antileukemic agent that inhibits de novopurine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. It is also an antitumor agent and induces apoptosis.

Solubility
Soluble in dilute solutions of alkali hydroxides, hot alcohol, and 1 N NaOH (50 mg/ml). Insoluble in water.

Notes
Store in cool, dry place, in well sealed container. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 6112-76-1
• Molecular Formula: C5H6N4OS
• Molecular Weight (g/mol): 170.19
• MDL Number: MFCD03854445,MFCD01461928
• InChI Key: WFFQYWAAEWLHJC-UHFFFAOYSA-N
• Synonym: 6-mercaptopurine monohydrate, 6-mercaptopurine hydrate, mercaptopurine monohydrate, mercaptopurine hydrate, 6h-purine-6-thione, 1,7-dihydro-, monohydrate, 6,7-dihydro-3h-purine-6-thione hydrate, purine-6-thiol monohydrate, 1,7-dihydro-6h-purine-6-thione monohydrate, purine-6-thiol, monohydrate, unii-e7wed276i5
• PubChem CID: 2724350
• ChEBI: CHEBI:31822
• IUPAC Name: 3,7-dihydropurine-6-thione;hydrate
• SMILES: O.S=C1N=CNC2=C1NC=N2

• Melting Point: ∼315°C (decomposition)
• Quantity: 1 g
• Beilstein: 4012091
• Merck Index: 14,5871
• Solubility Information: Soluble in dilute solutions of alkali hydroxides,hot alcohol,and 1 N NaOH (50mg/ml). Insoluble in water.
• Formula Weight: 170.19 (152.17 Anhydrous)
• Percent Purity: 98%
• Chemical Name or Material: 6-Mercaptopurine monohydrate

RUO – Research Use Only