6-Thioguanine, 98%, Thermo Scientific Chemicals

Description

6-Thioguanine acts as an antineoplastic and purine antimetabolite. It is also useful as an inhibition of stimulated expression of TNF-related apoptosis-inducing ligand (TRAIL) protein. It is involved in the treatment of acute leukemias and Psoriasis. Further, it is used for the treatment of ulcerative colitis and autoimmune diseases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dilute solutions of alkali hydroxides and hot alcohol. Insoluble in water.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 154-42-7
• Molecular Formula: C5H5N5S
• Molecular Weight (g/mol): 167.19
• MDL Number: MFCD00233553
• InChI Key: WYWHKKSPHMUBEB-UHFFFAOYSA-N
• Synonym: 6-thioguanine, thioguanine, tioguanine, 2-amino-6-mercaptopurine, 6-mercaptoguanine, tioguanin, tabloid, lanvis, 2-amino-6-purinethiol, 2-aminopurine-6-thiol
• PubChem CID: 2723601
• ChEBI: CHEBI:9555
• SMILES: NC1=NC(=S)C2=C(N1)N=CN2

• Melting Point: >360°C
• Assay Percent Range: 0.98
• Quantity: 1 g
• UN Number: UN2811
• Beilstein: 157765
• Merck Index: 14,9337
• Solubility Information: Soluble in dilute solutions of alkali hydroxides and hot alcohol. Insoluble in water.
• IUPAC Name: 2-amino-3,7-dihydropurine-6-thione
• Formula Weight: 167.19
• Percent Purity: 98%
• Chemical Name or Material: 6-Thioguanine

Safety and Handling

Product Identifier

• 6-Thioguanine

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Germ cell mutagenicity Category 2

Hazard Statement

• H301-Toxic if swallowed.
• H341-Suspected of causing genetic defects.

Precautionary Statement

• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /

Supplemental information

• MIXTURE LIST-Contains : Thioguanine

RUO – Research Use Only