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8-CPT-2Me-cAMP, sodium salt, Tocris Bioscience™
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Quantity:
1 mg
Description
Selective activator of Epac, the cAMP-sensitive guanine nucleotide-exchange factor for Rap1 and Rap2. Activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 > 10 μM). Stimulates Epac-mediated Ca2+-mediated Ca2+ release in pancreatic β-cells in vitro. Cell permeable analog (Cat. No. 4853) also available.
Specifications
Specifications
CAS | 634207-53-7 |
Molecular Formula | C17H17ClN5NaO6PS |
Quantity | 1 mg |
Synonym | 8-cpt-2me-camp, sodium salt |
InChI Key | IORFFVUNBNOFAO-KHXPSBENSA-N |
SMILES | COC1C2C(COP(=O)(O2)O)OC1N3C4=C(C(=NC=N4)N)N=C3SC5=CC=C(C=C5)Cl.[Na] |
IUPAC Name | 9-[(4aR,6R,7R,7aR)-2-hydroxy-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-8-(4-chlorophenyl)sulfanylpurin-6-amine;sodium |
Molecular Weight (g/mol) | 508.826 |
PubChem CID | 131856562 |
Formula Weight | 507.82 |
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