A 967079, Tocris Bioscience™

Description

Selective TRPA1 channel blocker

Selective TRPA1 channel blocker (IC50 values are 67 and 289 nM at human and rat TRPA1 receptors respectively). Displays 1000-fold selectivity for TRPA1 over other TRP channels, and is >150-fold selective over 75 other ion channels, enzymes and G-protein-coupled receptors. Exhibits analgesic effects in a rat osteoarthritic pain model.

Specifications

Chemical Identifiers

• CAS: 1170613-55-4
• Molecular Formula: C12H14FNO
• Molecular Weight (g/mol): 207.248
• InChI Key: HKROEBDHHKMNBZ-YAERWZOESA-N
• Synonym: 1e,3e-1-4-fluorophenyl-2-methyl-1-penten-3-one oxime
• PubChem CID: 122197682
• IUPAC Name: N-[(E)-1-(4-fluorophenyl)-2-methylpent-1-en-3-ylidene]hydroxylamine
• SMILES: CCC(=NO)C(=CC1=CC=C(C=C1)F)C

• Quantity: 10 mg
• Formula Weight: 207.24
• Percent Purity: >98%
• Chemical Name or Material: A 967079