Tocris Bioscience™ A12B4C3

Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor

Brand:  Tocris Bioscience™ 5097/50

Product Code. 18728788

Description

A12B4C3 is a potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor (IC50 = 60 nM). Displays no effect on calcineurin, protein PP-1 or APTX. Interrupts DNA repair and enhances radiosensitivity of human A549 lung carcinoma and MDA-MB-231 cells.

Specifications

• Purity: >98%
• Product Type: A12B4C3
• Inhibitors: A12B4C3

• Quantity: 50 mg
• Molecular Weight (g/mol): 534.65

For Research Use Only