Tocris Bioscience™ AA 147

ER proteostasis regulator

Brand:  Tocris Bioscience™ 6759/5

Product Code. 18075912

Description

AA 147 is an endoplasmic reticulum (ER) proteostasis regulator. Activates the ATF6 transcriptional program independently of ER stress and/or global UPR activation. Selectively reduces secretion of amyloidogenic transthyretin (TTR) from HepG2 cells. Reduces amyloidogenic immunoglobulin light chain (ALLC) secretion from ALMC-2 cells (EC50 = 1.1 μM).

Specifications

• Chemical Name or Material: N-(2-Hydroxy-5-methylphenyl)benzenepropanamide
• Quantity: 5 mg
• Formula Weight: 255.31

• CAS: 393121-74-9
• Molecular Formula: C₁₆H₁₇NO₂
• Purity: 98%