Tocris Bioscience™ Ac-FLTD-CMK

Potent and selective inhibitor of caspases 1, 5 and 4

Brand:  Tocris Bioscience™ 7242/1

Product Code. 18035742

Description

Ac-FLTD-CMK is a potent and selective inhibitor of caspases 1, 5 and 4 (IC50 values = 46.7 nM, 0.33 μM, 1.49 μM, respectively), and inhibits murine caspase-11 at 10 μM. Ac-FLTD-CMK inhibits cleavage of gasdermin D by caspases, suppresses pyroptosis and reduces IL-1β release in macrophages.

Specifications

• CAS: 2376255-48-8
• Target: Caspase Inhibitors
• Purity: 0.95

• Quantity: 1 mg
• Molecular Formula: C₂₆H₃₇ClN₄O₈