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  7. Adapalene, Tocris Bioscience™

Adapalene, Tocris Bioscience™

Catalog Number 18085572
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
106685-40-9
C28H28O3
412.529
LZCDAPDGXCYOEH-UHFFFAOYSA-N
adapalene, differin, adapalenum, adapaleno, adapaleno inn-spanish, adaferin, 6-3-adamantan-1-yl-4-methoxyphenyl-2-naphthoic acid, adapalenum inn-latin, differine, 6-3-1-adamantyl-4-methoxyphenyl-2-naphthoic acid
60164
CHEBI:31174
6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid
COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5
This item is not returnable. View return policy
106685-40-9
C28H28O3
412.529
LZCDAPDGXCYOEH-UHFFFAOYSA-N
adapalene, differin, adapalenum, adapaleno, adapaleno inn-spanish, adaferin, 6-3-adamantan-1-yl-4-methoxyphenyl-2-naphthoic acid, adapalenum inn-latin, differine, 6-3-1-adamantyl-4-methoxyphenyl-2-naphthoic acid
60164
CHEBI:31174
6-[3-(1-adamantyl)-4-methoxyphenyl]naphthalene-2-carboxylic acid
COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5

Description

RARβ and RARγ agonist

Retinoic acid analog that is a RARβ and RARγ agonist (AC50 values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RARγ, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cell in vitro. Displays comedolytic activity.
Quantity 50 mg
Formula Weight 412.52
Percent Purity >98%
Chemical Name or Material Adapalene
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