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Aiolos Monoclonal Antibody (8B2), eFluor™ 660, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£111.00 - £298.00
Specifications
Antigen | Aiolos |
---|---|
Clone | 8B2 |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | eFluor 660 |
Description
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.Specifications
Aiolos | |
Flow Cytometry | |
eFluor 660 | |
Mouse | |
Mouse | |
22780 | |
IgG1 κ | |
Affinity chromatography | |
Ikzf3 |
8B2 | |
Monoclonal | |
Liquid | |
RUO | |
O08900 | |
Ikzf3 | |
Primary | |
Antibody |
For Research Use Only.