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ALDH3A1 Monoclonal Antibody (OTI1C6), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA525098
This item is not returnable.
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Description
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorption of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.Specifications
ALDH3A1 | |
Monoclonal | |
0.96 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P30838 | |
ALDH3A1 | |
Full length human recombinant protein of ALDH3A1 produced in HEK293T cell | |
100μL | |
Primary | |
Human | |
Antibody | |
IgG2a |
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
OTI1C6 | |
Unconjugated | |
ALDH3A1 | |
Ahd4; Ahd-4; AHDC; Ahd-c; alcohol dehydrogenase family 3, subfamily A1; Aldd; Aldehyde dehydrogenase (Ahd-c); Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family member A1; aldehyde dehydrogenase 3 family, member A1; aldehyde dehydrogenase 3 family, memberA1; aldehyde dehydrogenase 3, stomach cytosolic (class 3); aldehyde dehydrogenase 3A1; aldehyde dehydrogenase 4; aldehyde dehydrogenase class 3; aldehyde dehydrogenase family 3 member A1; aldehyde dehydrogenase family 3 subfamily A1; aldehyde dehydrogenase family 3, member A1; aldehyde dehydrogenase family 3, subfamily A1; aldehyde dehydrogenase isozyme 3; aldehyde dehydrogenase type III; aldehyde dehydrogenase, dimeric NADP-preferring; Aldh; Aldh3; Aldh3a1; Aldh4; ALDHIII; BCP54; bovine corneal protein 54; corneal 15.8 kDa protein; corneal epithelium; corneal protein 54, transparentin; dehydrogenase 3, dimeric NAPD-prefering; dioxin-inducible aldehyde dehydrogenase 3; HTC-ALDH; MGC10406; stomach aldehyde dehydrogenase; transpar | |
Mouse | |
Affinity Chromatography | |
RUO | |
218 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |