Alloxan monohydrate, 98%, Thermo Scientific Chemicals

Description

Cytotoxic compound that causes oxidative base damage to nuclear DNAAlloxan monohydrate is used as a precursor to prepare purple dye murexide. It is also used in research models to induce diabetes and destroy beta cells. Further, it is a strong oxidizing agent and it forms a hemiacetal with its reduced reaction product dialuric acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cytotoxic compound that causes oxidative base damage to nuclear DNAAlloxan monohydrate is used as a precursor to prepare purple dye murexide. It is also used in research models to induce diabetes and destroy beta cells. Further, it is a strong oxidizing agent and it forms a hemiacetal with its reduced reaction product dialuric acid.

Solubility
Soluble in water, ethanol, acetone, glacial acetic acid and methanol. Slightly soluble in chloroform, petroleum ether, toluene, ethyl acetate and acetic anhydride. Insoluble in ether.

Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 3237-50-1
• Molecular Formula: C4H4N2O5
• Molecular Weight (g/mol): 160.085
• MDL Number: MFCD00149399
• InChI Key: ZIIHZVKHFWOENY-UHFFFAOYSA-N
• Synonym: barbituric acid, 5,5-dihydroxy, 2,4,6 1h,3h,5h-pyrimidinetrione, 5,5-dihydroxy, unii-o2aap9f8b6, 5,5-dihydroxybarbituric acid, ccris 5957, mesoxalylurea monohydrate, 2,4,5,6 1h,3h-pyrimidinetetrone hydrate, 5,5-dihydroxyperhydropyrimidinetrione, 5,5-dihydroxy-2,4,6 1h,3h,5h-pyrimidinetrione, o2aap9f8b6
• PubChem CID: 312231
• IUPAC Name: 5,5-dihydroxy-1,3-diazinane-2,4,6-trione
• SMILES: C1(=O)C(C(=O)NC(=O)N1)(O)O

• Melting Point: ∼260°C (decomposition)
• Beilstein: 5309394
• Merck Index: 14,282
• Formula Weight: 160.09 (142.07 Anhydrous)
• Percent Purity: 98%
• Quantity: 250 g
• Chemical Name or Material: Alloxan monohydrate

RUO – Research Use Only