Thermo Scientific Chemicals alpha-Apo-oxytetracycline, 'can be used as secondary standard'

Description

Alpha-Apo-oxytetracycline, CAS # 18695-01-7, is considered a metabolite formed from oxytetracycline, a member of the tetracycline family, and displays antibiotic activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information
• Alpha-Apo-oxytetracycline is a degradation product of oxytetracycline. When this degradation occurs, two isomers are generated, β- and α -apo-oxytetracycline

Applications
• Alpha-Apo-oxytetracycline compound presents antibiotic activity
• It promotes the inhibition of the growth of aerobic sludge bacteria, Pseudomonas, Agrobacterium, Moraxella, Bacillus, as well as tetracycline-resistant strains of E. coli

Specifications

• CAS: 18695-01-7
• Melting Point: 200.0°C
• Color: Khaki
• Infrared Spectrum: Authentic
• Assay Percent Range: 80% min. (as is,calculated)
• Packaging: Glass bottle
• Molecular Formula: C₂₂H₂₂N₂O₈
• MDL Number: MFCD00062827
• Quantity: 100 mg
• Merck Index: 10, 6846
• Specific Rotation: − 64.00
• Synonym: beta-apo-oxytetracycline, alpha-apo-oxytetracycline, alpha-apooxytetracycline, alpha-apoterramycin, beta-apo oxytetracycline, 2z-2-amino hydroxy methylidene-5-4,5-dihydroxy-9-methyl-3-oxo-1h-benzo f 2 benzofuran-1-yl-4-dimethylamino-6-hydroxycyclohexane-1,3-dione, 4-1,3-dihydro-4,5-dihydroxy-9-methyl-3-oxonaphtho 2,3-c furan-1-yl-3-dimethylamino-2,5-dihydroxy-6-oxo-1-cyclohexene-1-carboxamide, 4-4,5-dihydroxy-9-methyl-3-oxo-1,3-dihydronaphtho 2,3-c furan-1-yl-3-dimethylamino-2,5-dihydroxy-6-oxocyclohex-1-ene-1-carboxamide, 4-4,5-dihydroxy-9-methyl-3-oxohydrobenzo f isobenzofuranyl-3-dimethylamino-2,5-dihydroxy-6-oxocyclohex-1-enecarboxamide, 4-4,5-dihydroxy-9-methyl-3-oxo-1h-naphtho 2,3-c furan-1-yl-3-dimethylamino-2,5-dihydroxy-6-oxocyclohex-1-ene-1-carboxamide
• Solubility Information: Solubility in water: insoluble. Other solubilities: soluble in alkaline solution and ammonia
• InChI Key: DRKMHDAKULCOKQ-UHFFFAOYSA-N
• SMILES: CC1=C2C(OC(=O)C2=C(C3=C1C=CC=C3O)O)C4C(C(=C(C(=O)C4O)C(=O)N)O)N(C)C
• IUPAC Name: 4-(4,5-dihydroxy-9-methyl-3-oxo-1H-benzo[f][2]benzofuran-1-yl)-3-(dimethylamino)-2,5-dihydroxy-6-oxocyclohexene-1-carboxamide
• Molecular Weight (g/mol): 442.39
• PubChem CID: 54710410
• Formula Weight: 442.39
• Percent Purity: ≥97.0% (on anhydrous substance), ≥80 wt% (as is, calculated)(HPLC)
• Physical Form: Crystalline Powder
• Chemical Name or Material: α-Apo-oxytetracycline, (can be used as secondary standard)

Safety and Handling

Product Identifier

• alfa-Apo-oxytetracycline

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Reproductive toxicity Category 2

Hazard Statement

• H361d-Suspected of damaging the unborn child.
• H319-Causes serious eye irritation.

Precautionary Statement

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

RUO – Research Use Only