Amlodipine besylate, Tocris Bioscience™

Description

CaV1.x blocker

L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC50 = 25 μM).

Specifications

• CAS: 111470-99-6
• Molecular Formula: C26H31ClN2O8S
• Quantity: 50 mg
• Synonym: amlodipine besylate, amlodipine besilate, cardiorex, amlodipine benzenesulfonate, istin, amdepin, amdipin, amlodin, amlogard, amlopin
• InChI Key: ZPBWCRDSRKPIDG-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O
• IUPAC Name: benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
• Molecular Weight (g/mol): 567.05
• PubChem CID: 60496
• ChEBI: CHEBI:2669
• Formula Weight: 567.05
• Percent Purity: 98%
• Chemical Name or Material: Amlodipine besylate