Angiotensin I (human), Thermo Scientific Chemicals

Description

Angiotensin I (human) stimulates the release of aldosterone, another hormone, from the adrenal cortex. It acts as a precursor to angiotensin II. It acts as endogenous peptide substrate for angiotensin converting enzyme (ACE), precursor to the vasoconstrictor peptide angiotensin II

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Angiotensin I (human) stimulates the release of aldosterone, another hormone, from the adrenal cortex. It acts as a precursor to angiotensin II. It acts as endogenous peptide substrate for angiotensin converting enzyme (ACE), precursor to the vasoconstrictor peptide angiotensin II

Solubility
Soluble to 1 mg/ml in water.

Notes
Protect from heat. Incompatible with heat and oxidizing agents. Store at 4°C.

Specifications

Chemical Identifiers

• CAS: 484-42-4
• Molecular Formula: C62H89N17O14
• Molecular Weight (g/mol): 1296.50
• MDL Number: MFCD00133091
• InChI Key: ORWYRWWVDCYOMK-HBZPZAIKSA-N
• Synonym: angiotensin i, human angiotensin i, angiotensin i human, 5-ile-angiotensin i, angiotensin i rat, angiotensin i mouse, angiotensin 1 human, angiotensin i human, mouse, rat, pepsitensin, ile5-angiotensin i
• PubChem CID: 3081372
• ChEBI: CHEBI:2718
• IUPAC Name: (2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-[(diaminomethylidene)amino]pentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanamido]-3-(1H-imidazol-5-yl)propanamido]-4-methylpentanoic acid
• SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(C)C)C(O)=O

• Color: White
• Quantity: 5 mg
• Solubility Information: Soluble to 1mg/ml in water.
• Formula Weight: 1296.5
• Physical Form: Powder
• Chemical Name or Material: Angiotensin I (human)

RUO – Research Use Only