Anisomycin, Tocris Bioscience™

Description

JNK, SAPK and p38 activator

Anisomycin is a protein synthesis inhibitor (blocks translation). Potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. Acts as a potent signaling agonist to selectively elicit homologous desensitization of immediate early gene induction (c-fos, fosB, c-jun, junB and junD).

Specifications

Chemical Identifiers

• CAS: 22862-76-6
• Molecular Formula: C14H19NO4
• Molecular Weight (g/mol): 265.31
• MDL Number: MFCD00077650
• InChI Key: YKJYKKNCCRKFSL-BFHYXJOUSA-N
• Synonym: (2R,3S,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate
• PubChem CID: 253602
• ChEBI: CHEBI:338412
• IUPAC Name: (2S,3R,4R)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl acetate
• SMILES: COC1=CC=C(C[C@@H]2NC[C@@H](O)[C@@H]2OC(C)=O)C=C1

• Type: Anisomycin
• Formula Weight: 265.31
• Percent Purity: >98%
• Quantity: 10 mg
• Chemical Name or Material: Anisomycin