Thrombomodulin Monoclonal Antibody (141C01 (1009)), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA511454

Product Code. 11324453

Description

MA5-11454 targets CD141 in IHC (P), FACS and ICC/IF applications and shows reactivity with Human and Rat samples. The MA5-11454 immunogen is recombinant protein encoding the six repeated EGF domains of human thrombomodulin.

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

Specifications

• Antigen: Thrombomodulin
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: tissue culture supernatant with 0.09% sodium azide
• Gene Accession No.: P07204
• Gene Symbols: THBD
• Immunogen: Recombinant protein encoding the six repeated EGF domains of human thrombomodulin
• Regulatory Status: RUO
• Gene ID (Entrez): 7056, 83580
• Content And Storage: 4° C
• Form: Liquid

• Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)
• Clone: 141C01 (1009)
• Conjugate: Unconjugated
• Gene: THBD
• Gene Alias: AHUS6; AI385582; BDCA3; BDCA-3; CD141; CD141 antigen; DC141; fetomodulin; sCD141; snoRNA MBII-339; soluble CD141; THBD; THPH12; THRM; thrombomdulin; thrombomodulin; thrombomodulin precursor; TM
• Host Species: Mouse
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1 κ