ID2 Monoclonal Antibody (4E12G5), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA517095

Product Code. 15378020

Description

MA5-17095 targets ID2 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples. The MA5-17095 immunogen is purified recombinant fragment of human ID2 (amino acids: 1-134) expressed in E. Coli. MA5-17095 detects ID2 which has a predicted molecular weight of approximately 15kDa.

The inhibitor of DNA binding 2 (ID2) protein is essential for promoting the development of a number of cell types including natural killer cell, erythroid precursors, as well as, CD8+ and CD4+ T-cell. A lack of ID2 promotes B-cell development. The chief role of this protein is to associate with ubiquitously-expressed E proteins, and other proteins of the basic helix-loop-helix (HLH) family, preventing them from binding to DNA and activating transcription. Activation of ID2 is critical for the development of the natural killer cell lineage.

Specifications

• Antigen: ID2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q02363
• Gene Symbols: ID2
• Immunogen: Purified recombinant fragment of human ID2 (amino acids: 1-134) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 4E12G5
• Conjugate: Unconjugated
• Gene: ID2
• Gene Alias: Ac2-300; AI255428; bHLHb26; C78922; cell growth-inhibiting gene 8; class B basic helix-loop-helix protein 26; DNA-binding protein inhibitor ID2; DNA-binding protein inhibitor ID-2; GIG8; helix-loop-helix protein ID2; Id2; Id-2; ID2A; ID2H; Idb2; Inhibitor of differentiation 2; inhibitor of DNA binding 2; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; inhibitor of DNA binding 2, HLH protein; MGC26389; OTTHUMP00000140258; OTTHUMP00000200297
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 3398
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid