IL-12 (p40) Mouse anti-Human, Unlabeled, Clone: C8.3, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 551227

Product Code. 15856578

Description

The C8.3 antibody reacts with human IL-12 p40 subunit but not IL-12 p70 heterodimer or IL-12 p35 monomer. The immunogen used to generate the C8.3 hybridoma was the purified p40 subunit of human IL-12. The C8.3 antibody has been reported not to bind p40 chain when it is complexed to p35 (i.e., the p70 heterodimer). The combination of anti-p40 antibodies, C8.3 and C8.6 , has been reported to yield an assay for detecting only free p40 chain, and specifically not the p70 heterodimer. It has been reported that activated PBMC produce an excess of the
free p40 protein over the p70 heterodimer.

Host Species: Mouse
Clone: C8.3
Isotype: IgG1
Species Reactivity: Human
Immunogen: Purified human IL-12 p40 subunit

ELISA

Specifications

• Antigen: IL-12 (p40)
• Classification: Monoclonal
• Concentration: 1.0mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Purified human IL-12 p40 subunit
• Quantity: 1 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: ELISA
• Clone: C8.3
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

For Research Use Only.